ABCC1 p.Phe728Cys
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PMID: 21589945
[PubMed]
Klepsch F et al: "Exhaustive sampling of docking poses reveals binding hypotheses for propafenone type inhibitors of P-glycoprotein."
No.
Sentence
Comment
244
Loo et al. also demonstrated that binding of vinblastine, cyclosporin A and rhodamine B could prevent the formation of a cross-link between L339C and F728C, suggesting that the ligands are at least partially located between these two residues [52].
X
ABCC1 p.Phe728Cys 21589945:244:150
status: NEW
No.
Sentence
Comment
373
Introduction of the I306R(TM5) mutation into mutant L339C/F728C reduced its apparent affinity for vinblastine more than 60-fold but had little effect on its apparent affinity for rhodamine.
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ABCC1 p.Phe728Cys 18328253:373:58
status: NEW