ABCMdb

ABCC8 p.Leu1210Arg

None has been submitted yet.

Publications

PMID: 2964367 [PubMed] Eid P et al: "Interferon removes its own receptors as it blocks the division of Daudi cells."

No. Sentence Comment

86 (A) The neutral cxtract from Daudi cells treated with IFN at 75 pM for 30 min; (B) as in A but with a monoclonal antibody to IFN present; (C)profile for IFN and antibody alone; (D) same as A but with the digitonin at pH 3 (0.1 M acetic acid); (E)same as A but with 1 mM 1,4-dithioerythritolpresent; (F) extract from untreated Daudi cells to which IFN and 1,4-dithioerythritol had been added together; (G) extract from untreated Daudi cells to which IFN has been added alone; (H) extract from untreated mouse cells (L1210R) to which IFN has been added alone approximately linear on log M , of the protein markers. Login to comment
116 Fig. 2G (Daudi extract) and Fig. 2H (mouse L1210R extract) suggest that scrambling is probably unrelated to receptor binding as the R strain of the mouse lymphoma line L1210 is resistant to IFN and possesses no receptors [20]. Login to comment