ABCC8 p.Asp854Glu

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PMID: 16442101 [PubMed] Frelet A et al: "Insight in eukaryotic ABC transporter function by mutation analysis."
No. Sentence Comment
155 The model described by Campbell et al. [98] suggested that mutation E1506 (NBD2) in SUR1 to aspartate reduces ATP hydrolysis, whereas D854E (NBD1) enhances the hydrolytic activity.
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ABCC8 p.Asp854Glu 16442101:155:134
status: NEW
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PMID: 14593442 [PubMed] Campbell JD et al: "Potassium channel regulation."
No. Sentence Comment
77 Our model suggests that mutation of E1506 in NBD2 to aspartate might reduce ATP hydrolysis, whereas the D854E mutation in site 1 might enhance hydrolytic activity.
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ABCC8 p.Asp854Glu 14593442:77:104
status: NEW
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