ABCC7 p.Ser753Ala
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No.
Sentence
Comment
497
The mutation 10SA-S753A eliminates much Additional evidence for phosphorylation-dependent control of CFTR channel activity comes from observa-of the residual PKA-dependent phosphorylation of the 10SA mutant and decreases the Po of the 10SA mutant by tions that there appear to be both high and low phosphorylation states correlating with a high and low Po (43, 64).40% (115).
X
ABCC7 p.Ser753Ala 9922375:497:18
status: NEW
PMID: 23760269
[PubMed]
Billet A et al: "Role of tyrosine phosphorylation in the muscarinic activation of the cystic fibrosis transmembrane conductance regulator (CFTR)."
No.
Sentence
Comment
102
Carbachol Stimulates CFTR through PKA and Non-PKA Signaling Pathways-To explore PKA-independent regulation of CFTR without using inhibitors that might have confounding effects on other pathways, we studied the activation of 15SA-CFTR (S422A/S660A/S670A/S686A/T690A/S700A/S712A/ S737A/S753A/S768A/T787A/T788A/S790A/S795A/S813A).
X
ABCC7 p.Ser753Ala 23760269:102:284
status: NEW