PMID: 9862704

Kuhns ST, Pease LR
A region of conformational variability outside the peptide-binding site of a class I MHC molecule.
J Immunol. 1998 Dec 15;161(12):6745-50., [PubMed]
Sentences
No. Mutations Sentence Comment
101 ABCB2 p.Leu156Tyr
X
ABCB2 p.Leu156Tyr 9862704:101:145
status: NEW
view ABCB2 p.Leu156Tyr details
 AF6-88.5 binding to spontaneous in vivo class I mutants Spontaneous Mutant Mutation Relative Percent AF6 Binding* Kb None 100 Kbm1 E152A, R155Y, L156Y 111 Kbm3 D77S, K89A 98 Kbm5 Y116F 106† Kbm8 Y22F, M23I, E24S, A30N 101 Kbm10 T163A, V165M, W167S, K173E, N174L 97 * The amount of Kb or mutant on the cell surface as determined with mAb 2813-3. Login to comment