PMID: 26601667

Okushin K, Tsutsumi T, Enooku K, Fujinaga H, Kado A, Shibahara J, Fukayama M, Moriya K, Yotsuyanagi H, Koike K
The intrahepatic expression levels of bile acid transporters are inversely correlated with the histological progression of nonalcoholic fatty liver disease.
J Gastroenterol. 2015 Nov 25., [PubMed]
Sentences
No. Mutations Sentence Comment
143 ABCB11 p.Asp482Gly
X
ABCB11 p.Asp482Gly 26601667:143:71
status: NEW
view ABCB11 p.Asp482Gly details
ABCB11 p.Glu297Gly
X
ABCB11 p.Glu297Gly 26601667:143:59
status: NEW
view ABCB11 p.Glu297Gly details
 In patients with either of the two common BSEP mutations p.E297G and p.D482G, 4-phenylbutyrate prolongs BSEP half-life in the canalicular membrane and, thus, increases the overall BSEP expression level [29]. Login to comment