PMID: 26250462

Salimizand H, Amini S, Abdi M, Ghaderi B, Azadi NA
Concurrent effects of ABCB1 C3435T, ABCG2 C421A, and XRCC1 Arg194Trp genetic polymorphisms with risk of cancer, clinical output, and response to treatment with imatinib mesylate in patients with chronic myeloid leukemia.
Tumour Biol. 2015 Aug 7., [PubMed]
Sentences
No. Mutations Sentence Comment
29 ABCG2 p.Gln141Lys
X
ABCG2 p.Gln141Lys 26250462:29:72
status: NEW
view ABCG2 p.Gln141Lys details
 Regarding ABCG2, one of the most important genetic variations is C421A (Q141K, rs2231142) which has been located on exon 5 and has a high association with BCRP activity [10-12]. Login to comment