PMID: 26244574

Chu YH, Li H, Tan HS, Koh V, Lai J, Phyo WM, Choudhury Y, Kanesvaran R, Chau NM, Toh CK, Ng QS, Tan PH, Chowbay B, Tan MH
Association of ABCB1 and FLT3 Polymorphisms with Toxicities and Survival in Asian Patients Receiving Sunitinib for Renal Cell Carcinoma.
PLoS One. 2015 Aug 5;10(8):e0134102. doi: 10.1371/journal.pone.0134102. eCollection 2015., [PubMed]
Sentences
No. Mutations Sentence Comment
102 ABCG2 p.Gln141Lys
X
ABCG2 p.Gln141Lys 26244574:102:386
status: NEW
view ABCG2 p.Gln141Lys details
 Genotype distribution Polymorphism rs number Variation na wt/wt wt/var var/var VAFe VEGFR2 1191 C/T rs2305948 V297I 94 64 30 0 0.160 (T) FLT3 738 T/C rs1933437 M227T 95 47 43 5 0.279 (C) ABCB1 1236 T/C rs1128503 G412G 93 35 49 9 0.360 (C) ABCB1 2677 G/TA rs2032582 A893S/T 96 25 44b 27c 0.375 (T); 0.135 (A) ABCB1 3435 C/T rs1045642 I1145I 96 34 50 12 0.385 (T) ABCG2 421 C/A rs2231142 Q141K 95 50 38 7 0.274 (A) BIM i2del d - i2del d 45 33 12 0 0.133 a Patients successfully genotyped. Login to comment