PMID: 26101157

Souza PS, Madigan JP, Gillet JP, Kapoor K, Ambudkar SV, Maia RC, Gottesman MM, Leung Fung K
Expression of the multidrug transporter P-glycoprotein is inversely related to that of apoptosis-associated endogenous TRAIL.
Exp Cell Res. 2015 Aug 15;336(2):318-28. doi: 10.1016/j.yexcr.2015.06.005. Epub 2015 Jun 19., [PubMed]
Sentences
No. Mutations Sentence Comment
82 ABCB1 p.Glu556Gln
X
ABCB1 p.Glu556Gln 26101157:82:64
status: NEW
view ABCB1 p.Glu556Gln details
 HeLa cell transductions with BacMam-Pgp virus wild-type and the E556Q/E1206Q mutant were performed as described previously [26,27]. Login to comment 175 ABCB1 p.Glu556Gln
X
ABCB1 p.Glu556Gln 26101157:175:183
status: NEW
view ABCB1 p.Glu556Gln details
 To further confirm the link between Pgp function and TRAIL expression, we compared TRAIL expression in HeLa cells transfected with wild-type ABCB1 and with a functional mutant ABCB1 (E556Q/E1206Q). Login to comment