PMID: 25792634

Trinh NT, Bilodeau C, Maille E, Ruffin M, Quintal MC, Desrosiers MY, Rousseau S, Brochiero E
Deleterious impact of Pseudomonas aeruginosa on cystic fibrosis transmembrane conductance regulator function and rescue in airway epithelial cells.
Eur Respir J. 2015 Jun;45(6):1590-602. doi: 10.1183/09031936.00076214. Epub 2015 Mar 18., [PubMed]
Sentences
No. Mutations Sentence Comment
39 ABCC7 p.Asn1303Lys
X
ABCC7 p.Asn1303Lys 25792634:39:165
status: NEW
view ABCC7 p.Asn1303Lys details
 Primary human airway cells were isolated from tissues obtained from non-CF and CF patients (with class II mutations, including ƊF508/ ƊF508 and ƊF508/N1303K, median age 23 years, mean forced expiratory volume in 1s of 82&#b1;9%) undergoing nasal polypectomy at CHUM (Montreal, QC, Canada) and CHU Sainte-Justine (Montreal, QC, Canada) hospitals [28], according to approved ethical protocols. Login to comment