PMID: 25468777

Grey Nee Cotte S, Salmen Nee Stroet A, von Ahsen N, Starck M, Winkelmann A, Zettl UK, Comabella M, Montalban X, Zipp F, Fleischer V, Kruse N, Gold R, Chan A
Lack of efficacy of mitoxantrone in primary progressive Multiple Sclerosis irrespective of pharmacogenetic factors: a multi-center, retrospective analysis.
J Neuroimmunol. 2015 Jan 15;278:277-9. doi: 10.1016/j.jneuroim.2014.11.017. Epub 2014 Nov 20., [PubMed]
Sentences
No. Mutations Sentence Comment
16 ABCG2 p.Gln141Lys
X
ABCG2 p.Gln141Lys 25468777:16:151
status: NEW
view ABCG2 p.Gln141Lys details
ABCG2 p.Val12Met
X
ABCG2 p.Val12Met 25468777:16:116
status: NEW
view ABCG2 p.Val12Met details
 Patients, material and methods After approval by local ethics committees and informed consent, genotyping for ABCG2 V12M (reference SNP rs2231137) and Q141K (rs2231142) and ABCB1 3435CNT (rs1045642) and 2677GNT (rs2032582) was performed using TaqManࡊ polymerase chain reaction Journal of Neuroimmunology 278 (2015) 277-279 Ìe; Corresponding author at: Department of Neurology, St. Josef-Hospital, Ruhr University Bochum, Gudrunstr. Login to comment