PMID: 24595600

Ferrari M, Guasti L, Maresca A, Mirabile M, Contini S, Grandi AM, Marino F, Cosentino M
Association between statin-induced creatine kinase elevation and genetic polymorphisms in SLCO1B1, ABCB1 and ABCG2.
Eur J Clin Pharmacol. 2014 May;70(5):539-47. doi: 10.1007/s00228-014-1661-6. Epub 2014 Mar 6., [PubMed]
Sentences
No. Mutations Sentence Comment
36 ABCG2 p.Gln141Lys
X
ABCG2 p.Gln141Lys 24595600:36:64
status: NEW
view ABCG2 p.Gln141Lys details
 Finally, in the ABCG2 gene, a relatively common SNP is C421A (p.Gln141Lys; rs2231142); this SNP occurs in 10-15 % of Caucasians and has been associated with reduced ABCG2 activity [36] and increased statin bioavailability [23]. Login to comment