PMID: 24338217

Zhao J, Li W, Zhu D, Yu Q, Zhang Z, Sun M, Cai S, Zhang W
Association of single nucleotide polymorphisms in MTHFR and ABCG2 with the different efficacy of first-line chemotherapy in metastatic colorectal cancer.
Med Oncol. 2014 Jan;31(1):802. doi: 10.1007/s12032-013-0802-6. Epub 2013 Dec 13., [PubMed]
Sentences
No. Mutations Sentence Comment
32 ABCG2 p.Gln141Lys
X
ABCG2 p.Gln141Lys 24338217:32:330
status: NEW
view ABCG2 p.Gln141Lys details
ABCG2 p.Val12Met
X
ABCG2 p.Val12Met 24338217:32:295
status: NEW
view ABCG2 p.Val12Met details
 Genotyping Genomic DNA was isolated from whole blood using the FUJIFILM DNA extraction kit. Based on previous published studies, the single nucleotide polymorphisms selected for testing were MTHFR 677C[T (rs1801133, Ala 222 Val) and 1298A[C (rs1801131, Glu 428 Ala), and ABCG2 34G[A (rs2231137, Val 12 Met) and 421C[A (rs2231142, Gln 141 Lys). Login to comment