PMID: 24076068

Harker M, Carvell AM, Marti VP, Riazanskaia S, Kelso H, Taylor D, Grimshaw S, Arnold DS, Zillmer R, Shaw J, Kirk JM, Alcasid ZM, Gonzales-Tanon S, Chan GP, Rosing EA, Smith AM
Functional characterisation of a SNP in the ABCC11 allele - effects on axillary skin metabolism, odour generation and associated behaviours.
J Dermatol Sci. 2014 Jan;73(1):23-30. doi: 10.1016/j.jdermsci.2013.08.016. Epub 2013 Sep 10., [PubMed]
Sentences
No. Mutations Sentence Comment
1 ABCC11 p.Gly180Arg
X
ABCC11 p.Gly180Arg 24076068:1:169
status: NEW
view ABCC11 p.Gly180Arg details
 Introduction The gene ABCC11, encodes an ATP-driven efflux pump for amphipathic anions [1,2], that displays a single nucleotide polymorphism (SNP), 538G!A, leading to a G180R substitution in the corresponding protein. Login to comment 8 ABCC11 p.Gly180Arg
X
ABCC11 p.Gly180Arg 24076068:8:412
status: NEW
view ABCC11 p.Gly180Arg details
 The extent to which the SNP (R180) variant of ABCC11 Journal of Dermatological Science 73 (2014) 23-30 A R T I C L E I N F O Article history: Received 18 March 2013 Received in revised form 1 August 2013 Accepted 30 August 2013 Keywords: Glutamine conjugate Malodour Odoriferous Skin microbiome Skin metabolomics Volatiles A B S T R A C T Background: A single nucleotide polymorphism (SNP), 538G!A, leading to a G180R substitution in the ABCC11 gene results in reduced concentrations of apocrine derived axillary odour precursors. Login to comment