PMID: 23934280

Lee RJ, Chen B, Doghramji L, Adappa ND, Palmer JN, Kennedy DW, Cohen NA
Vasoactive intestinal peptide regulates sinonasal mucociliary clearance and synergizes with histamine in stimulating sinonasal fluid secretion.
FASEB J. 2013 Dec;27(12):5094-103. doi: 10.1096/fj.13-234476. Epub 2013 Aug 9., [PubMed]
Sentences
No. Mutations Sentence Comment
182 ABCC7 p.Trp1282*
X
ABCC7 p.Trp1282* 23934280:182:222
status: NEW
view ABCC7 p.Trp1282* details
ABCC7 p.Asn1303Lys
X
ABCC7 p.Asn1303Lys 23934280:182:229
status: NEW
view ABCC7 p.Asn1303Lys details
ABCC7 p.Gly542*
X
ABCC7 p.Gly542* 23934280:182:253
status: NEW
view ABCC7 p.Gly542* details
 To further test the role of CFTR in this synergistic fluid secretion, we measured basal and stimulated ASL heights in ALI cultures derived from CF patient cells (nafd;3 patients; genotypes were èc;F508/èc;F508, W1282X/N1303K, and èc;F508/G542X). Login to comment