PMID: 23827224

Feher A, Juhasz A, Laszlo A, Pakaski M, Kalman J, Janka Z
Association between the ABCG2 C421A polymorphism and Alzheimer's disease.
Neurosci Lett. 2013 Aug 29;550:51-4. doi: 10.1016/j.neulet.2013.06.044. Epub 2013 Jul 1., [PubMed]
Sentences
No. Mutations Sentence Comment
39 ABCG2 p.Gln141Lys
X
ABCG2 p.Gln141Lys 23827224:39:62
status: NEW
view ABCG2 p.Gln141Lys details
 The C421A non-synonymous single nucleotide polymorphism (/SNP/Q141K, rs2231142) of the ABCG2 gene is reportedly associated with lower levels of protein expression, impaired transport, and enhanced susceptibility to ubiquitin-mediated proteosomal degradation [12,15,16,23,24]. Login to comment