PMID: 23742976

Tian Y, Qian S, Jiang Y, Shen Q, Zheng J, Zhou H, Zeng S
The interaction between human breast cancer resistance protein (BCRP) and five bisbenzylisoquinoline alkaloids.
Int J Pharm. 2013 Sep 10;453(2):371-9. doi: 10.1016/j.ijpharm.2013.05.053. Epub 2013 Jun 3., [PubMed]
Sentences
No. Mutations Sentence Comment
225 ABCG2 p.Arg482Thr
X
ABCG2 p.Arg482Thr 23742976:225:195
status: NEW
view ABCG2 p.Arg482Thr details
 Alqawi et al. reported that wild-type BCRP was more intensely photolabelled by iodoaryl-azido-rhodamine 123 (IAARh123, a photoreactive drug analog of rhodamine 123) than mutant BCRP in which the Arg 482 was mutated to Thr, but could not transport it (Alqawi et al., 2004). Login to comment