PMID: 23641929

Honorat M, Terreux R, Falson P, Di Pietro A, Dumontet C, Payen L
Localization of putative binding sites for cyclic guanosine monophosphate and the anti-cancer drug 5-fluoro-2'-deoxyuridine-5'-monophosphate on ABCC11 in silico models.
BMC Struct Biol. 2013 May 6;13:7. doi: 10.1186/1472-6807-13-7., [PubMed]
Sentences
No. Mutations Sentence Comment
100 ABCC11 p.Gly180Arg
X
ABCC11 p.Gly180Arg 23641929:100:155
status: NEW
view ABCC11 p.Gly180Arg details
ABCB4 p.Gly602Ala
X
ABCB4 p.Gly602Ala 23641929:100:99
status: NEW
view ABCB4 p.Gly602Ala details
 Insight in the impact of Glycine 180 polymorphism Gly180, found to be inside pocket 2, is prone to G602A SNP (single nucleotide polymorphism) inducing the Gly180Arg mutation which was correlated to earwax type [31], and to colostrum and sweat secretion defaults [32,33]. Login to comment 104 ABCC11 p.Gly180Arg
X
ABCC11 p.Gly180Arg 23641929:104:25
status: NEW
view ABCC11 p.Gly180Arg details
 The altered transport of Gly180Arg-mutant ABCC11 can be explained by the additional charge of arginine versus glycine. Login to comment