PMID: 22865455

Lai CY, Schwartz BE, Hsu MY
CD133+ melanoma subpopulations contribute to perivascular niche morphogenesis and tumorigenicity through vasculogenic mimicry.
Cancer Res. 2012 Oct 1;72(19):5111-8. doi: 10.1158/0008-5472.CAN-12-0624. Epub 2012 Aug 3., [PubMed]
Sentences
No. Mutations Sentence Comment
69 ABCB5 p.Ala375Pro
X
ABCB5 p.Ala375Pro 22865455:69:187
status: NEW
view ABCB5 p.Ala375Pro details
 Results CD133 expression in melanoma correlates with tumor progression in vivo Using flow cytometry, we identified CD133&#fe; fractions in 7 melanoma cell lines, including WM164, WM1617, A375P-5, and Figure 1. Login to comment 76 ABCB5 p.Ala375Pro
X
ABCB5 p.Ala375Pro 22865455:76:67
status: NEW
view ABCB5 p.Ala375Pro details
 Melanoma cell lines WM115 WM239A WM983A WM983C WM164 1205Lu WM1617 A375P-5 C b2;3 integrin CD133 Merged High MW PG CD133 A375 Nevi Primary metastatic Melanoma Patient samples (n = 7) % with CD133 + cells B Merged Neg. Cont. Neg. Cont. 400X 400X 35 4 3 2 1 0 CD133&#fe; Subset in Niche Formation and Melanoma Growth www.aacrjournals.org Cancer Res; 72(19) October 1, 2012 5113 2 isogenic cell pairs: WM115 (VGP)/WM239A (Met) and WM983A (VGP)/WM983C (Met), out of a total of (7/9) in vitro. Login to comment