PMID: 22593228

Wei Y, Ma Y, Zhao Q, Ren Z, Li Y, Hou T, Peng H
New use for an old drug: inhibiting ABCG2 with sorafenib.
Mol Cancer Ther. 2012 Aug;11(8):1693-702. Epub 2012 May 16., [PubMed]
Sentences
No. Mutations Sentence Comment
76 ABCG2 p.Arg482Gly
X
ABCG2 p.Arg482Gly 22593228:76:49
status: NEW
view ABCG2 p.Arg482Gly details
 Intracellular mitoxantrone accumulation in ABCG2 R482G-transfected stable HEK293 (HEK293/ ABCG2) cells and its corresponding ABCG2-negative vector-transfected control (HEK293/Vec) cells were measured in the presence or absence of sorafenib or Ko143 at 2.5 mmol/L. Login to comment 77 ABCG2 p.Arg482Gly
X
ABCG2 p.Arg482Gly 22593228:77:49
status: NEW
view ABCG2 p.Arg482Gly details
 Intracellular mitoxantrone accumulation in ABCG2 R482G-transfected stable HEK293 (HEK293/ ABCG2) cells and its corresponding ABCG2-negative vector-transfected control (HEK293/Vec) cells were measured in the presence or absence of sorafenib or Ko143 at 2.5 mmol/L. Login to comment