PMID: 22565184

Hamajima N, Naito M, Okada R, Kawai S, Yin G, Morita E, Higashibata T, Tamura T, Nakagawa H, Matsuo H, Mori A, Wakai K
Significant interaction between LRP2 rs2544390 in intron 1 and alcohol drinking for serum uric acid levels among a Japanese population.
Gene. 2012 Jul 15;503(1):131-6. Epub 2012 Apr 28., [PubMed]
Sentences
No. Mutations Sentence Comment
31 ABCG2 p.Gln141Lys
X
ABCG2 p.Gln141Lys 22565184:31:248
status: NEW
view ABCG2 p.Gln141Lys details
ABCG2 p.Gln126*
X
ABCG2 p.Gln126* 22565184:31:231
status: NEW
view ABCG2 p.Gln126* details
 This study aimed to confirm the association of SUA with LRP2 rs2544390 at intron 1 and rs3755166 at the promoter region in a Japanese population, after eliminating the effects of SLC22A12 W258X SLC2A9 rs11722228 at intron 8, ABCG2 Q126X, and ABCG2 Q141K on SUA (Hamajima et al., 2011a, 2011b; Matsuo et al., 2009; Tabara et al., 2010). Login to comment 110 ABCG2 p.Gln141Lys
X
ABCG2 p.Gln141Lys 22565184:110:204
status: NEW
view ABCG2 p.Gln141Lys details
ABCG2 p.Gln126*
X
ABCG2 p.Gln126* 22565184:110:193
status: NEW
view ABCG2 p.Gln126* details
 The difference in the mean SUA between CC and TT was 0.08 mg/dL among males with creatinineb2 mg/dL (G1 in Table 3), which was smaller than those among SLC22A12 W258X, SLC2A9 rs11722228, ABCG2 Q126X, and Q141K. Login to comment