PMID: 22426010

Heffeter P, Pirker C, Kowol CR, Herrman G, Dornetshuber R, Miklos W, Jungwirth U, Koellensperger G, Keppler BK, Berger W
Impact of terminal dimethylation on the resistance profile of alpha-N-heterocyclic thiosemicarbazones.
Biochem Pharmacol. 2012 Jun 15;83(12):1623-33. Epub 2012 Mar 15., [PubMed]
Sentences
No. Mutations Sentence Comment
47 ABCG2 p.Arg482Thr
X
ABCG2 p.Arg482Thr 22426010:47:262
status: NEW
view ABCG2 p.Arg482Thr details
ABCG2 p.Arg482Thr
X
ABCG2 p.Arg482Thr 22426010:47:263
status: NEW
view ABCG2 p.Arg482Thr details
 Center, Kansas State University, USA), the small cell lung carcinoma cell line GLC-4 and its ABCC1- and LRP-overexpressing subline GLC-4/adr (from E.G. deVries, Groningen, The Netherlands); the breast adenocarcinoma cell line MDA-MB-231 with its respective ABCG2(R482T)-transfected subclone MDA-MB-231/bcrp (from D. Ross, University of Maryland, Greenbaum Cancer Centre, USA), the non-small cell lung carcinoma cell line SW1573 with its ABCC1- and LRP-overexpressing subline 2R120 as well as its ABCB1- and ABCC1-overexpressing subline 2R160 (H. Broxterman, Department of Medical Oncology, Free University Hospital, Amsterdam, The Netherlands). Login to comment