PMID: 22056557

Fulop K, Jiang Q, Wetering KV, Pomozi V, Szabo PT, Aranyi T, Sarkadi B, Borst P, Uitto J, Varadi A
ABCC6 does not transport vitamin K3-glutathione conjugate from the liver: relevance to pathomechanisms of pseudoxanthoma elasticum.
Biochem Biophys Res Commun. 2011 Nov 25;415(3):468-71. Epub 2011 Oct 28., [PubMed]
Sentences
No. Mutations Sentence Comment
92 ABCC1 p.Gly771Asp
X
ABCC1 p.Gly771Asp 22056557:92:103
status: NEW
view ABCC1 p.Gly771Asp details
As controls we tested Sf9 vesicles overexpressing the human ABCC1 or an inactive mutant form of ABCC1 (G771D, see [28]). Login to comment
106 ABCC1 p.Gly771Asp
X
ABCC1 p.Gly771Asp 22056557:106:13
status: NEW
view ABCC1 p.Gly771Asp details
ABCC1, ABCC1 G771D mutant and ABCC6 were expressed in Sf9 insect cells. Login to comment
112 ABCC1 p.Gly771Asp
X
ABCC1 p.Gly771Asp 22056557:112:26
status: NEW
view ABCC1 p.Gly771Asp details
The transport rate of the G771D inactive mutant (Ç) compared to wild type (d) at 60, 250 or 500 nM concentrations is shown in the insert. Login to comment