PMID: 22038265

Anzai N, Jutabha P, Amonpatumrat-Takahashi S, Sakurai H
Recent advances in renal urate transport: characterization of candidate transporters indicated by genome-wide association studies.
Clin Exp Nephrol. 2012 Feb;16(1):89-95. Epub 2011 Nov 1., [PubMed]
Sentences
No. Mutations Sentence Comment
54 ABCG2 p.Gln141Lys
X
ABCG2 p.Gln141Lys 22038265:54:113
status: NEW
view ABCG2 p.Gln141Lys details
 Moreover, ABCG2 SNPs have been indicated to be an important factor for adverse drug reactions in patients, e.g., Q141K, the most extensively studied ABCG2 Apical Basolateral MCs UA URAT1 UA GLUT9 (URATv1) MCs UA URAT1 UA A B UA UA Apical Basolateral Proximal tubular cells Proximal tubular cells GLUT9 (URATv1) Fig. 2 Novel concept for idiopathic renal hypouricemia. Login to comment 60 ABCG2 p.Gln141Lys
X
ABCG2 p.Gln141Lys 22038265:60:27
status: NEW
view ABCG2 p.Gln141Lys details
 Above-mentioned hypoactive Q141K protein is associated with hyperuricemia. Login to comment