PMID: 21655989

Lang T, Justenhoven C, Winter S, Baisch C, Hamann U, Harth V, Ko YD, Rabstein S, Spickenheuer A, Pesch B, Bruning T, Schwab M, Brauch H
The earwax-associated SNP c.538G>A (G180R) in ABCC11 is not associated with breast cancer risk in Europeans.
Breast Cancer Res Treat. 2011 Oct;129(3):993-9. Epub 2011 Jun 8., [PubMed]
Sentences
No. Mutations Sentence Comment
0 ABCC11 p.Gly180Arg
X
ABCC11 p.Gly180Arg 21655989:0:49
status: NEW
view ABCC11 p.Gly180Arg details
 BRIEF REPORT The earwax-associated SNP c.538G>A (G180R) in ABCC11 is not associated with breast cancer risk in Europeans Thomas Lang • Christina Justenhoven • Stefan Winter • Christian Baisch • Ute Hamann • Volker Harth • Yon-Dschun Ko • Sylvia Rabstein • Anne Spickenheuer • Beate Pesch • Thomas Bru¨ning • Matthias Schwab • Hiltrud Brauch Received: 23 May 2011 / Accepted: 24 May 2011 / Published online: 8 June 2011 Ó Springer Science+Business Media, LLC. 2011 Abstract Genetic polymorphisms of human ABC-transporter genes have been suggested to modulate breast cancer risk in the general population. Login to comment 16 ABCC11 p.Gly180Arg
X
ABCC11 p.Gly180Arg 21655989:16:101
status: NEW
view ABCC11 p.Gly180Arg details
 A loss-of-function and nonsynonymous SNP (c.538G[A; rs17822931) encoding the amino acid substitution G180R of ABCC11 recently has been shown to underlie the formation of cerumen, i.e. either wet or dry earwax. Login to comment