PMID: 21540052

Pinto RD, Pereira PJ, dos Santos NM
Transporters associated with antigen processing (TAP) in sea bass (Dicentrarchus labrax, L.): molecular cloning and characterization of TAP1 and TAP2.
Dev Comp Immunol. 2011 Nov;35(11):1173-81. Epub 2011 Apr 19., [PubMed]
Sentences
No. Mutations Sentence Comment
135 ABCB3 p.Thr293Pro
X
ABCB3 p.Thr293Pro 21540052:135:26
status: NEW
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 A mutation in mouse TAP2 (T293P) is responsible for a reduction in TAP2 protein levels in the recent Jasmine strain (Theodoratos et al., 2010). Login to comment 139 ABCB3 p.Ala374Asp
X
ABCB3 p.Ala374Asp 21540052:139:49
status: NEW
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 In human TAP2, a single amino acid substitution (A374D), changes the preference for the transported peptide (Armandola et al., 1996). Login to comment 161 ABCB2 p.Gln277Cys
X
ABCB2 p.Gln277Cys 21540052:161:58
status: NEW
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 Mutations on highly conserved residues of CH1/CL1 (except Q277C) and of sensor region (G282C, I284C, R287C) interfered with and drastically affected transport, respectively. Login to comment 162 ABCB2 p.Gln277Cys
X
ABCB2 p.Gln277Cys 21540052:162:58
status: NEW
view ABCB2 p.Gln277Cys details
 Mutations on highly conserved residues of CH1/CL1 (except Q277C) and of sensor region (G282C, I284C, R287C) interfered with and drastically affected transport, respectively. Login to comment