PMID: 21187511

Ota I, Sakurai A, Toyoda Y, Morita S, Sasaki T, Chishima T, Yamakado M, Kawai Y, Ishidao T, Lezhava A, Yoshiura K, Togo S, Hayashizaki Y, Ishikawa T, Ishikawa T, Endo I, Shimada H
Association between breast cancer risk and the wild-type allele of human ABC transporter ABCC11.
Anticancer Res. 2010 Dec;30(12):5189-94., [PubMed]
Sentences
No. Mutations Sentence Comment
2 ABCC11 p.Gly180Arg
X
ABCC11 p.Gly180Arg 21187511:2:104
status: NEW
view ABCC11 p.Gly180Arg details
 It was recently found that earwax type is determined by a single nucleotide polymorphism (SNP), 538G>A (Gly180Arg), in ABCC11. Login to comment 15 ABCC11 p.Gly180Arg
X
ABCC11 p.Gly180Arg 21187511:15:136
status: NEW
view ABCC11 p.Gly180Arg details
 Recent studies (4, 5) have provided evidence that the type of earwax is determined by one single nucleotide polymorphism (SNP), 538G>A (Gly180Arg), in the ATP-binding cassette (ABC) transporter ABCC11 located on human chromosome 16q12.1 (6). Login to comment 78 ABCC11 p.Gly180Arg
X
ABCC11 p.Gly180Arg 21187511:78:47
status: NEW
view ABCC11 p.Gly180Arg details
 Among those SNPs, one SNP (rs17822931; 538G>A, Gly180Arg) is thought to be a clinically important polymorphism that may related with breast cancer risk. Login to comment