PMID: 20883210

Iwata R, Baur K, Stieger B, Mertens JC, Daly AK, Frei P, Braun J, Vergopoulos A, Stickel F, Sabrane K, Martin IV, Schmitt J, Goetze O, Day CP, Mullhaupt B, Geier A
A common polymorphism in the ABCB11 gene is associated with advanced fibrosis in hepatitis C but not in non-alcoholic fatty liver disease.
Clin Sci (Lond). 2011 Apr;120(7):287-96., [PubMed]
Sentences
No. Mutations Sentence Comment
55 ABCB11 p.Val444Ala
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ABCB11 p.Val444Ala 20883210:55:56
status: NEW
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 In these cohorts, genotyping of the SNP ABCB11 1331T>C (V444A, rs2287622) was performed with the TaqMan SNP genotyping assay C_16182459_10, genotyping of the SNP NR1H4 - 1G>T with a custom-made TaqMan SNP genotyping assay SNP-FXR3-FXR3 [18] (Applied Biosystems). Login to comment 132 ABCB11 p.Val444Ala
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ABCB11 p.Val444Ala 20883210:132:27
status: NEW
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 The common ABCB11 1331T>C (V444A) polymorphism in the BSEP gene, which is encountered in about half of the Caucasian population, has been linked to increased serum bile acid levels in patients with cholestasis of pregnancy [13]. Login to comment