PMID: 20876799

Mi YJ, Liang YJ, Huang HB, Zhao HY, Wu CP, Wang F, Tao LY, Zhang CZ, Dai CL, Tiwari AK, Ma XX, To KK, Ambudkar SV, Chen ZS, Fu LW
Apatinib (YN968D1) reverses multidrug resistance by inhibiting the efflux function of multiple ATP-binding cassette transporters.
Cancer Res. 2010 Oct 15;70(20):7981-91. Epub 2010 Sep 28., 2010-10-15 [PubMed]
Sentences
No. Mutations Sentence Comment
116 ABCG2 p.Arg482Gly
X
ABCG2 p.Arg482Gly 20876799:116:81
status: VERIFIED
view ABCG2 p.Arg482Gly details
 It should be noted that S1-M1-80, but not the wild-type ABCG2, overexpressed the R482G variant, which can transport Rho 123 (39). Login to comment 117 ABCG2 p.Arg482Gly
X
ABCG2 p.Arg482Gly 20876799:117:81
status: NEW
view ABCG2 p.Arg482Gly details
 It should be noted that S1-M1-80, but not the wild-type ABCG2, overexpressed the R482G variant, which can transport Rho 123 (39). Login to comment