PMID: 20472486

Merriman TR, Dalbeth N
The genetic basis of hyperuricaemia and gout.
Joint Bone Spine. 2011 Jan;78(1):35-40. Epub 2010 May 15., [PubMed]
Sentences
No. Mutations Sentence Comment
84 ABCG2 p.Gln141Lys
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ABCG2 p.Gln141Lys 20472486:84:66
status: VERIFIED
view ABCG2 p.Gln141Lys details
 ABCG2 A non-synonymous single nucleotide polymorphism (rs2231142; Q141K) is the likely etiological variant explaining the association of ABCG2 with gout [11,24]. Login to comment 152 ABCG2 p.Gln141Lys
X
ABCG2 p.Gln141Lys 20472486:152:32
status: VERIFIED
view ABCG2 p.Gln141Lys details
 Strong association of the ABCG2 Q141K variant with gout has been reported in people of Western Pacific (Samoa, Tonga) ancestry (OR > 2.5) but not in people of Eastern Pacific ancestry (Cook Island and New Zealand M¯aori) (OR < 1.4) [28]. Login to comment