PMID: 19631619

Tai LM, Reddy PS, Lopez-Ramirez MA, Davies HA, Male DK, Loughlin AJ, Romero IA
Polarized P-glycoprotein expression by the immortalised human brain endothelial cell line, hCMEC/D3, restricts apical-to-basolateral permeability to rhodamine 123.
Brain Res. 2009 Oct 6;1292:14-24. Epub 2009 Jul 23., [PubMed]
Sentences
No. Mutations Sentence Comment
245 ABCG2 p.Arg482Thr
X
ABCG2 p.Arg482Thr 19631619:245:0
status: NEW
view ABCG2 p.Arg482Thr details
 Arginine482 to threonine mutation in the breast cancer resistance protein ABCG2 inhibits rhodamine 123 transport while increasing binding. Login to comment