PMID: 19197249

Tripodi G, Citterio L, Kouznetsova T, Lanzani C, Florio M, Modica R, Messaggio E, Hamlyn JM, Zagato L, Bianchi G, Staessen JA, Manunta P
Steroid biosynthesis and renal excretion in human essential hypertension: association with blood pressure and endogenous ouabain.
Am J Hypertens. 2009 Apr;22(4):357-63. Epub 2009 Feb 5., [PubMed]
Sentences
No. Mutations Sentence Comment
60 ABCB1 p.Ser400Asn
X
ABCB1 p.Ser400Asn 19197249:60:835
status: NEW
view ABCB1 p.Ser400Asn details
 A = 0.17; G = 0.83 SLCO4C1 rs3811976 5q21.1 101599098 Untranslated 3'-UTR A = 0.82; G = 0.08 SLCO4C1 rs6596425 5q21.1 101603285 Intron C = 0.18; G = 0.82 SLCO4C1 rs10515323 5q21.1 101611553 Intron C = 0.13; G = 0.87 SLCO4C1 rs174414 5q21.1 101620640 Intron A = 0.35; G = 0.65 SLCO4C1 rs370176 5q21.1 101623456 Intron A = 0.78; G = 0.22 SLCO4C1 rs2600831 5q21.1 101633969 Intron A = 0.58;T = 0.42 SLCO4C1 rs2548724 5q21.1 101648072 Intron A = 0.20; G = 0.80 SLCO4C1 rs709369 5q21.1 101652234 Intron A = 0.52; G = 0.48 SLCO4C1 rs841922 5q21.1 101658594 Intron A = 0.27; C = 0.73 MDR1 rs17064 7q21.12 86971405 Untranslated 3'-UTR A = 0.07;T = 0.93 MDR1 rs1045642 7q21.12 86976580 Synonymous Ile1145 T = 0.52; C = 0.48 MDR1 rs2032582 7q21.12 86998553 Nonsynonymous Ala893Ser G = 0.54;T = 0.46 MDR1 rs2229109 7q21.12 87017744 Nonsynonymous Ser400Asn A = 0.05; G = 0.95 SNP ID is a GenBank ID number (NCBI), gene map position and SNP function were taken from the most recent human genome sequence assembly hg18 (NCBI Build 36.1). Login to comment