PMID: 19056916

Giri N, Agarwal S, Shaik N, Pan G, Chen Y, Elmquist WF
Substrate-dependent breast cancer resistance protein (Bcrp1/Abcg2)-mediated interactions: consideration of multiple binding sites in in vitro assay design.
Drug Metab Dispos. 2009 Mar;37(3):560-70. Epub 2008 Dec 4., [PubMed]
Sentences
No. Mutations Sentence Comment
185 ABCG2 p.Arg482Gly
X
ABCG2 p.Arg482Gly 19056916:185:72
status: VERIFIED
view ABCG2 p.Arg482Gly details
 Clark et al. (2006) reported that the binding of [3 H]daunomycin to the R482G isoform of BCRP was complete, partial, or not significant, depending on the competing BCRP substrate used to examine this binding interaction. Login to comment