PMID: 18668431

Zhou SF
Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition.
Xenobiotica. 2008 Jul;38(7-8):802-32., [PubMed]
Sentences
No. Mutations Sentence Comment
296 ABCB1 p.Asn21Asp
X
ABCB1 p.Asn21Asp 18668431:296:44
status: NEW
view ABCB1 p.Asn21Asp details
ABCB1 p.Phe103Leu
X
ABCB1 p.Phe103Leu 18668431:296:94
status: NEW
view ABCB1 p.Phe103Leu details
 Exon 2 contains a polymorphism that changes Asn-21 to Asp, and the mutation at exon 5 changes Phe-103 to Leu. Login to comment 298 ABCB1 p.Ser400Asn
X
ABCB1 p.Ser400Asn 18668431:298:59
status: NEW
view ABCB1 p.Ser400Asn details
 A G1199A polymorphism is located at exon 11, which changes Ser-400 to Asn. Login to comment