PMID: 18334915

Crettol S, Venetz JP, Fontana M, Aubert JD, Ansermot N, Fathi M, Pascual M, Eap CB
Influence of ABCB1 genetic polymorphisms on cyclosporine intracellular concentration in transplant recipients.
Pharmacogenet Genomics. 2008 Apr;18(4):307-15., [PubMed]
Sentences
No. Mutations Sentence Comment
135 ABCB1 p.Asn21Asp
X
ABCB1 p.Asn21Asp 18334915:135:30
status: NEW
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 In this study, ABCB1 61A > G (N21D), 1236C > Tand 2677G > T (A893S) SNPs did not influence cyclosporine intracellular and blood concentrations. Login to comment 136 ABCB1 p.Ser400Asn
X
ABCB1 p.Ser400Asn 18334915:136:28
status: NEW
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 In contrast, the 1199G > A (S400N) and 3435C > T SNPs significantly influenced cyclosporine concentration in opposite directions. Login to comment