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PMID: 18156365
Callaghan R, Crowley E, Potter S, Kerr ID
P-glycoprotein: so many ways to turn it on.
J Clin Pharmacol. 2008 Mar;48(3):365-78. Epub 2007 Dec 21.,
[PubMed]
Sentences
No.
Mutations
Sentence
Comment
174
ABCC3 p.Pro450Arg
X
ABCC3 p.Pro450Arg 18156365:174:250
status:
NEW
view ABCC3 p.Pro450Arg details
ABCC3 p.Pro450Arg
X
ABCC3 p.Pro450Arg 18156365:174:267
status:
NEW
view ABCC3 p.Pro450Arg details
ABCC3 p.Pro450Arg
X
ABCC3 p.Pro450Arg 18156365:174:284
status:
NEW
view ABCC3 p.Pro450Arg details
ABCC3 p.Pro450Arg
X
ABCC3 p.Pro450Arg 18156365:174:301
status:
NEW
view ABCC3 p.Pro450Arg details
In the same study, one such compound, the anti-neoplastic ET-743, EXPRESSION OF P-GLYCOPROTEIN REVIEW/DRUG METABOLISM AND TRANSPORT 373 CAR CYP2B ABCC1-C3 PXR CYP3A ABCC1-C2 ABCB1 AhR CYP1A GST UDP-GT GST UDP-GT FXR LXR CYP7A ABCB11 ABCC2 GST UDP-GT
P450R
GST UDP-GT
P450R
GST UDP-GT
P450R
GST UDP-GT
P450R
ABCA1 ABCG1 ABCG5 ABCG8 Figure 4.
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