PMID: 18054347

Hira A, Watanabe H, Maeda Y, Yokoo K, Sanematsu E, Fujii J, Sasaki J, Hamada A, Saito H
Role of P-glycoprotein in accumulation and cytotoxicity of amrubicin and amrubicinol in MDR1 gene-transfected LLC-PK1 cells and human A549 lung adenocarcinoma cells.
Biochem Pharmacol. 2008 Feb 15;75(4):973-80. Epub 2007 Oct 30., [PubMed]
Sentences
No. Mutations Sentence Comment
239 ABCG2 p.Gln141Lys
X
ABCG2 p.Gln141Lys 18054347:239:180
status: NEW
view ABCG2 p.Gln141Lys details
 [29] Imai Y, Nakane M, Kage K, Tsukahara S, Ishikawa E, Tsuruo T, et al. C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance. Login to comment