PMID: 17952118

Vilgelm A, Wei JX, Piazuelo MB, Washington MK, Prassolov V, El-Rifai W, Zaika A
DeltaNp73alpha regulates MDR1 expression by inhibiting p53 function.
Oncogene. 2008 Apr 3;27(15):2170-6. Epub 2007 Oct 22., 2008-04-03 [PubMed]
Sentences
No. Mutations Sentence Comment
38 ABCB1 p.Leu322Pro
X
ABCB1 p.Leu322Pro 17952118:38:30
status: NEW
view ABCB1 p.Leu322Pro details
 Interestingly, mutant DNp73a (L322P) was unable to increase the MDR1 mRNA level. Login to comment 121 ABCB1 p.Leu322Pro
X
ABCB1 p.Leu322Pro 17952118:121:22
status: NEW
view ABCB1 p.Leu322Pro details
 Interestingly, DNp73a(L322P) mutant, which has an impaired ability to inhibit p53, was unable to activate mdr1 gene transcription (Zaika et al., 2002). Login to comment