PMID: 17785426

Zhang Y, Wang H, Unadkat JD, Mao Q
Breast cancer resistance protein 1 limits fetal distribution of nitrofurantoin in the pregnant mouse.
Drug Metab Dispos. 2007 Dec;35(12):2154-8. Epub 2007 Sep 4., [PubMed]
Sentences
No. Mutations Sentence Comment
174 ABCG2 p.Gln141Lys
X
ABCG2 p.Gln141Lys 17785426:174:72
status: VERIFIED
view ABCG2 p.Gln141Lys details
 Thus, the fetuses of pregnant women with BCRP natural variants, such as Q141K, that display lower transport activity (Imai et al., 2002) may have an increased risk for potential NFT toxicity. Login to comment