PMID: 17487233

Yeboah D, Sun M, Kingdom J, Baczyk D, Lye SJ, Matthews SG, Gibb W
Expression of breast cancer resistance protein (BCRP/ABCG2) in human placenta throughout gestation and at term before and after labor.
Can J Physiol Pharmacol. 2006 Dec;84(12):1251-8., [PubMed]
Sentences
No. Mutations Sentence Comment
52 ABCG2 p.Arg482Gly
X
ABCG2 p.Arg482Gly 17487233:52:135
status: NEW
view ABCG2 p.Arg482Gly details
 For instance, the wild type BCRP is unable to transport anthracycline, doxorubicin, or rhodamine but mutant BCRP in which threonine or glycine replaces arginine at position 482 transports all 3 substrates (Allen and Schinkel 2002; Sarkadi et al. 2004; Volk et al. 2002). Login to comment