PMID: 17376120

Simon C, Stieger B, Kullak-Ublick GA, Fried M, Mueller S, Fritschy JM, Wieser HG, Pauli-Magnus C
Intestinal expression of cytochrome P450 enzymes and ABC transporters and carbamazepine and phenytoin disposition.
Acta Neurol Scand. 2007 Apr;115(4):232-42., [PubMed]
Sentences
No. Mutations Sentence Comment
27 ABCC2 p.Cys1515Tyr
X
ABCC2 p.Cys1515Tyr 17376120:27:194
status: NEW
view ABCC2 p.Cys1515Tyr details
ABCC2 p.Val1188Glu
X
ABCC2 p.Val1188Glu 17376120:27:176
status: NEW
view ABCC2 p.Val1188Glu details
The role of ABCC2 polymorphisms on MRP2 expression is less well established, but recent data indicate that hepatic MRP2 expression is influenced by two SNPs in positions 1188 (V1188E) and 1515 (C1515Y) of the MRP2 protein. Login to comment