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PMID: 17021796
Aleksandrov AA, Aleksandrov LA, Riordan JR
CFTR (ABCC7) is a hydrolyzable-ligand-gated channel.
Pflugers Arch. 2007 Feb;453(5):693-702. Epub 2006 Sep 26.,
[PubMed]
Sentences
No.
Mutations
Sentence
Comment
144
ABCC7 p.Arg555Lys
X
ABCC7 p.Arg555Lys 17021796:144:103
status:
NEW
view ABCC7 p.Arg555Lys details
In addition to these theoretical concerns, it is noted that the effect of the NBD1 signature mutation,
R555K
on the rate of opening is quite different from that reported previously by Teem et al. [74] and as measured in our laboratory.
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244
ABCC7 p.Gly551Asp
X
ABCC7 p.Gly551Asp 17021796:244:100
status:
NEW
view ABCC7 p.Gly551Asp details
Howell LD, Borchardt R, Cohn JA (2000) ATP hydrolysis by a CFTR domain: pharmacology and effects of
G551D
mutation.
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