PMID: 16690355

Modok S, Mellor HR, Callaghan R
Modulation of multidrug resistance efflux pump activity to overcome chemoresistance in cancer.
Curr Opin Pharmacol. 2006 Aug;6(4):350-4. Epub 2006 May 11., [PubMed]
Sentences
No. Mutations Sentence Comment
46 ABCG2 p.Arg482Thr
X
ABCG2 p.Arg482Thr 16690355:46:81
status: VERIFIED
view ABCG2 p.Arg482Thr details
 Ortataxel also inhibits MRP1, whereas both compounds are ineffective against the R482T BCRP isoform [15]. Login to comment