ABCMdb

PMID: 16313984

Martin M, Gonzalez P, Reguero JJ, Batalla A, Garcia Castro M, Coto E, Moris C
ABCA1 polymorphisms and prognosis after myocardial infarction in young patients.
Int J Cardiol. 2006 Jun 16;110(2):267-8. Epub 2005 Nov 28., [PubMed]

Sentences

No. Mutations Sentence Comment

3 ABCA1 p.Ile883Met We have analysed three polymorphisms of the ABCA1 gene (-477C/T, R219 K, and I883M) in a cohort of young male survivors of myocardial infarction in order to know their influence in long-term prognosis. Login to comment 9 ABCA1 p.Ile883Met ABCA1 p.Ile883Met ABCA1 p.Arg219Lys ABCA1 p.Arg219Lys In order to know whether there is a relationship between ABCA1 polymorphisms and prognosis after myocardial infarction in young patients, we have analysed three polymorphisms in ABCA1 gene (À477C/T, R219K, I883M) in a cohort of young male survivors of first myocardial infarction. Login to comment 19 ABCA1 p.Ile883Met ABCA1 p.Ile883Met ABCA1 p.Arg219Lys Table 1 Frequency of genotypes of ABCA1 gene in study and control group Genotypes Patients (%) Controls (%) p ABCA1 R219K RR 48 49 ns RK 42 40 KK 10 11 ABCA1 À477C/T CC 24 30 ns TC 50 50 TT 26 20 ABCA1 I883M AA 69 80 ns AG/GG 31 20 International Journal of Cardiology 110 (2006) - 268 www.elsevier.com/locate/ijcard Fasting blood samples were drawn for measurements of total plasma cholesterol, HDL-C and triglycerides in the first 24 h after admission. Login to comment