PMID: 16271446

Smith NF, Figg WD, Sparreboom A
Pharmacogenetics of irinotecan metabolism and transport: an update.
Toxicol In Vitro. 2006 Mar;20(2):163-75. Epub 2005 Nov 3., [PubMed]
Sentences
No. Mutations Sentence Comment
998 ABCG2 p.Gln141Lys
X
ABCG2 p.Gln141Lys 16271446:998:110
status: NEW
view ABCG2 p.Gln141Lys details
ABCG2 p.Gln141Lys
X
ABCG2 p.Gln141Lys 16271446:998:144
status: NEW
view ABCG2 p.Gln141Lys details
 Of these, the most extensively studied is the 421C > A transversion, which results in an amino acid change of glutamine to lysine at codon 141 (Q141K). Login to comment