PMID: 16246729

Kleizen B, van Vlijmen T, de Jonge HR, Braakman I
Folding of CFTR is predominantly cotranslational.
Mol Cell. 2005 Oct 28;20(2):277-87., [PubMed]
Sentences
No. Mutations Sentence Comment
92 ABCC7 p.Pro205Ser
X
ABCC7 p.Pro205Ser 16246729:92:254
status: NEW
view ABCC7 p.Pro205Ser details
 Altogether these results validate our proteolysis assay as a measure for CFTR folding and conformation in semipermeabilized cells, which was confirmed further by the subtle changes we detected in two CF patient-related mutants, CFTR èc;F508 and CFTR P205S (our unpublished data). Login to comment 93 ABCC7 p.Pro205Ser
X
ABCC7 p.Pro205Ser 16246729:93:255
status: NEW
view ABCC7 p.Pro205Ser details
 Altogether these results validate our proteolysis assay as a measure for CFTR folding and conformation in semipermeabilized cells, which was confirmed further by the subtle changes we detected in two CF patient-related mutants, CFTR ⌬F508 and CFTR P205S (our unpublished data). Login to comment