PMID: 16141795

Wang D, Johnson AD, Papp AC, Kroetz DL, Sadee W
Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability.
Pharmacogenet Genomics. 2005 Oct;15(10):693-704., [PubMed]
Sentences
No. Mutations Sentence Comment
190 ABCB1 p.Thr1236Cys
X
ABCB1 p.Thr1236Cys 16141795:190:243
status: NEW
view ABCB1 p.Thr1236Cys details
ABCB1 p.Thr1236Cys
X
ABCB1 p.Thr1236Cys 16141795:190:315
status: NEW
view ABCB1 p.Thr1236Cys details
 When Fig. 5 1.8 *** *** ### *** ### *** ### *** ### *** ### *** ### *** ### ## 3435C/3435T 1236C/1236T 1.6 1.6 1.4 1.4 1.2 1.2 DNA-48hRNA-8hDNA-8h RNA-48h 1.0 1.0 0.8 0.8 0.6 0.6 0.4 1.8 2677G/2677T 1.6 1.4 1.2 1.0 0.8 0.6 0.4 0.4 *13 3435C > T1236C > T/3435C > T2677G > T/3435C > T *13 1236C > T 1236C > T/2677G > T1236C > T/3435C > T *13 2677G > T 1236C > T/2677G > T 2677G > T/3435C > T (a) (b) (c) Differential mRNA expression between ABCB1*1 and different ABCB1 variants after co-transfection into CHO cells. Login to comment