PMID: 15955871

Hirano M, Maeda K, Matsushima S, Nozaki Y, Kusuhara H, Sugiyama Y
Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin.
Mol Pharmacol. 2005 Sep;68(3):800-7. Epub 2005 Jun 13., [PubMed]
Sentences
No. Mutations Sentence Comment
224 ABCG2 p.Gln141Lys
X
ABCG2 p.Gln141Lys 15955871:224:129
status: VERIFIED
view ABCG2 p.Gln141Lys details
 The elimination of diflomotecan from plasma has been found to be delayed in patients with frequently observed SNP in BCRP (C421A/Q141K) (Sparreboom et al., 2004). Login to comment