PMID: 15735043

Nakamura Y, Oka M, Soda H, Shiozawa K, Yoshikawa M, Itoh A, Ikegami Y, Tsurutani J, Nakatomi K, Kitazaki T, Doi S, Yoshida H, Kohno S
Gefitinib ("Iressa", ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, reverses breast cancer resistance protein/ABCG2-mediated drug resistance.
Cancer Res. 2005 Feb 15;65(4):1541-6., 2005-02-15 [PubMed]
Sentences
No. Mutations Sentence Comment
42 ABCG2 p.Arg482Thr
X
ABCG2 p.Arg482Thr 15735043:42:46
status: VERIFIED
view ABCG2 p.Arg482Thr details
 The transfectants have a mutant form of BCRP (R482T; ref. 25). Login to comment