PMID: 15516692

Ueda T, Brenner S, Malech HL, Langemeijer SM, Perl S, Kirby M, Phang OA, Krouse AE, Donahue RE, Kang EM, Tisdale JF
Cloning and functional analysis of the rhesus macaque ABCG2 gene. Forced expression confers an SP phenotype among hematopoietic stem cell progeny in vivo.
J Biol Chem. 2005 Jan 14;280(2):991-8. Epub 2004 Oct 30., 2005-01-14 [PubMed]
Sentences
No. Mutations Sentence Comment
198 ABCG2 p.Arg482Gly
X
ABCG2 p.Arg482Gly 15516692:198:42
status: VERIFIED
view ABCG2 p.Arg482Gly details
 Further, coexpression of gp91phox and the R482G variant of ABCG2 corrected the phenotype of gp91phox knockout cells and protected the transduced cells from the toxic effects of mitoxantrone (39). Login to comment